Scientists Are Looking At Man’s Best Friend To Help Crack The Code Of Aging

One of life’s biggest tragedies is that you usually outlive you dog. In a pooch’s ten or so years on the planet, their tail-wagging, head-tilting, paw-offering sweetness nuzzles its way into your heart as nothing else can. So before we say that painful final goodbye, it would be comforting to know they helped change history.

Well, scientists are embarking on a research study to debunk the secrets of aging. To do it, they needed animals that mimic the human process of growing older, and luckily, their dogs nudged them in the right direction. As subjects in the largest aging research project, dogs are expected to change the way life ends as we currently know it.

The University of Washington is home base to an exciting scientific venture into one of life’s greatest barriers — aging. While many have tried to turn back the hands of Father Time’s clock, this study has the legs to be the real deal.

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With a 15 million dollar grant from The National Council on Aging, Professors Daniel Promislow and Matt Kaeberlein teamed up with Chief Veterinarian Dr. Katie Creevy to study roughly 10,000 dogs over a ten-year period.

University of Washington Aging / Twitter

Before we open the door to immortality or add on a few more years to the average life expectancy, we first have to take a closer look at an animal with near-human aging experiences. That’s where dogs come in.

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Turns out, you have a lot more in common with man’s best friend than you initially thought. As dogs grow older, they are at risk of developing and succumbing to the same diseases as elderly humans.

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Studying how diseases, like cancer and heart disease, and degenerative issues, like arthritis and incontinence, affect dogs provides answers on how to treat humans with the same conditions. Age-related health problems impact dogs across all breeds, which is another advantage of canine research subjects.

Pet Plan

As of 2019, there are 340 official dog breeds of all shapes, colors, and sizes — a scientific researcher’s dream. The larger the sample size, the more accurate the findings. Ideally, they’d monitor humans as they age but dogs really speed up the process.

Creature Comforts Cheshire

By the end of a dog’s first year of life, it’s aged roughly 15 human years. Researchers get a front row seat to the aging cycle, starting with newborn subjects, along through, hopefully, their geriatric years, all within the span of a decade.


We have to hand it to dogs: they’ve mastered the art of being present in the moment. As Daniel Promislow explained, “They live in our environment and in many ways, they experience our environment more intensely than we do.”


From how they flop around in the freshly cut grass, to their long days spent in near solitude while their humans are at work, free to touch, sniff, or taste whatever, a dog’s paws-on approach to life only adds to their value as sample subjects.

Ball Walk Park

The process is easy for the subject pups. All that’s needed is a cheek swab. It’s the same as other popular at-home genetic testing kits for breed determination, owners take the sample from their dog’s mouths and mail it to the lab.

Science Mag

Once at the lab, the cost of sequencing the dog’s genome is covered through the project. Analyzing the dog’s DNA patterns helps scientists pinpoint trends. In short, they can see whether certain DNA compositions are more susceptible to specific health problems.


In their findings, they are taking note of particular environmental factors. They narrowed it down to a list of possible health influencers: water and air quality, exposure to pesticides, and carpeted or hardwood floored homes.

Dogs Naturally Magazine

The researcher’s long term goal for the study is to determine whether these same environmental factors make a difference in human aging, too. If something poses a threat to a dog’s longevity, so it will for it’s human, or so they will find out.

NY Times

A smaller percentage of the test dogs, around 4-5%, make up a clinical study for a relatively new wonder drug that’s supposed to be an all-around health booster. Nope, they aren’t lapping up elixir from the fountain of youth, but potentially, it could have similar effects.

Crusoe Dachshund / Twitter

It’s called rapamycin and is largely used in cancer treatment and organ transplants. So far, it’s been tested on worms, flies, and mice. In the limited studies of the drug, it’s shown to have increased the overall health and life spans of the subjects. 

New Atlas

If our dogs are living longer, that gives us more time to spoil them rotten. So if you’re reading this while petting your pup, guess what? Just like all dogs go to heaven, they are also all welcome to participate in the study. 

USA Today

Prospective participants only need to fill out a brief survey. From there, the Dog Aging Project will reach out if your pet meets the criteria. Which would be worth the effort if Baxter’s genetic information helps cure an infectious disease.

Washington Post

The benefit isn’t just for a greater understanding of aging. Scientists can spot trends in the data and provide dog parents with the best course of action for treating illness or offer insights into preventative care.

MPR News

Besides their short lifespans and unparalleled breed diversity, dogs were the ideal candidates for the aging study because they have the most advanced healthcare system of any other animal, besides humans, of course. We know quite a bit about man’s best friend.

Canine Cancer Center

So much so that they’ve determined why dogs do the things that they do. The experts didn’t stop at canines, either. In fact, a recent study into cats shed surprising insight on what they really thing of humans.


While you may think your cat, who just hissed at you for no rhyme or reason, is an arrogant rascal, the little ball of fur may see you as a special partner. Kitties are just full of surprises (and hairballs).

Social cognition regarding doggos has been studied for decades. By now we pretty much know that dogs are gentle social butterflies that this cruel world absolutely does not deserve. But the social cognition of cats has been neglected by the scientific community.

Since human babies, puppies, and baby monkeys have all showed signs of being securely or insecurely attached to their parents or guardians after a short period of separation, it got scientists thinking about how kittens would act in this type of situation.

Would separation anxiety plague little kittens? Well behavior studies would soon prove or reject the idea that cats could form secure bonds with their caregivers. Scientists at Oregon State University were on the case.

Washington Post

Just like dogs, cats have been witnessed living in harmonious social groupings, but that all depends on factors, such as early developmental occurrences, resource distribution, and social interaction experiences, according to scientific journal Current Biology.

In their study, those brainy scientists put kittens in their own rooms, with only a human caregiver to keep each one company. They spent exactly two minutes getting to know each other. The kittens were undoubtedly curious about their new surroundings.

Oregon State University

Said caregiver would then get up and exit the room for exactly two minutes, leaving the kitten alone. Those two minutes would give the new friends space to breathe and decompress from their introduction.

The Atlantic

Sure enough, two minutes later, the caregiver would return to the room to greet the kitty once again. Their behavior during the reunion would be telling of their level of bonding. This process is called a “secure base test.”

The findings of the study were published in the scientific journal Cell Press, and the results may surprise you. There’s much to know about felines that probably escaped your mind. They’re complex beings!

“Like dogs, cats display social flexibility in regard to their attachments with humans,” Kristyn Vitale, study author and researcher at Oregon State University’s Human-Animal Interaction Lab, explained of cats’ behavioral habits. But not all cats have the same attachment style.

It turned out that 65% of cats are securely bonded with their owners! The findings show that the relationship continues to be constant in adulthood; the little kittens don’t typically outgrow their connection.

“We found that the attachment bond cats display toward their owners is very similar to the bond dogs share with their owners and even the bond human infants display toward their caretakers,” Krystin disclosed. And we thought they were so different.


On the other hand, some cats form insecure bonds with their owners. The insecurely attached cats showed signs of stress, which involved twitching tails, licking lips, and avoiding their owner at all costs. Somehow, we relate.

Oregon State University

Believe it or not, the felines that leaped into their owner’s lap, refusing to move, were also considered to be insecurely attached. This kind of behavior is an indicator of ambivalence. While they seemed mushy, there was a sense of crippling uncertainty.

Oregon State University

“Cats that are insecure seem to act aloof. There’s long been a biased way of thinking that all cats behave this way. But the majority of cats use their owner as a source of security,” Kristyn said.

Even the kittens that went through a 6-week socialization training course did not deviate from their bond with their master. Some bonds are just unbreakable by nature.

Kristyn even said that cats actually depend on their owners to help them when they feel stressed out. This whole time you’ve likely been thinking that good ol’ Sprinkles only required sustenance, but in reality, Sprinkles needs you for much more than that.

“We’re currently looking at several aspects of cat attachment behavior, including whether socialization and fostering opportunities impact attachment security in shelter cats,” Kristyn relayed regarding future studies.

The Office

We know it sounds bananas, but based on Krystin Vitale’s findings, your cat loves you more than you know. They may show their affection and gratitude for you in odd ways, but they’re not as antisocial and cold as you’d think.

Krystin Vitale’s secure base test findings only prove the unexpected emotional intelligence of our sassy, furry friends. You may think you have your feline figured out now, but there are plenty more surprises lurking behind those mysterious, golden cat eyes.

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We’re sure you’ve been perplexed by your cat’s uber-flexible body, and well, it’s no illusion. They actually have 53 vertebrae on their spines, while a human only has a measly 34. So stop trying to best your kitten during yoga — they’ve got you beat by 19 vertebrae!

2. If cat vs. dog intelligence has ever been debated, consider it resolved: Cats have 300 million neurons in their brains, while dogs have just 160 million. In fact, a cat’s brain is considered to be extremely similar to a human’s brain, so expect a feline uprising any day now.

3. Since whiskers detect distances and movements by the air’s vibration, they’re actually crucial to a cat’s survival in the outdoors. So don’t be too scared if your cat runs off — they have survival tools built right into their bodies!

4. What’s the deal with cats and catnip? Cats naturally have the scent of catnip binded to their nasal passages, so when they get a whiff of the herb, it stimulates the sensory receptors in their brains — and makes them act a little lovey-dovey.

5. It’s no secret that cats spend a majority of the day sleeping. We’re actually pretty jealous of just how long a cat can sleep for, which is at least 12-16 hours a day. Cats just don’t know how lucky they are! 

6. Did you know that cats have dominant paws? Females are more likely to use their right paws while males usually prefer their left. No word yet on if the whole “right brain, left brain” thing exists with cats!

7. The rumors are true, cats can change color! Well, maybe not in the way you’re thinking. Siamese cats have a gene modifier that technically makes them albino, but when they’re introduced to high temperatures, portions of their fur turns gray or even black. 

8. If you want your cat to stop leaping onto the kitchen table, try spraying them with lemon water. Cats are picky eaters and are especially sensitive to bitter and citrus-y flavors, so they’ll quickly learn to avoid the lemony spray. 

9. The next time your partner scolds you for taking too long in the shower, bring up this fact: cats spend 30%-50% of the day cleaning their bodies! Much like us with showering, grooming improves a cat’s circulation and prevents any unseemly odors. 

10. A purring cat can be totally soothing when you’re in a bad mood, but the sound has other surprising healing properties as well. Purring can be restorative to a cat’s health, and it even helps heal problems with bones and tissues. 

11. Be careful when considering a major lifestyle change with your cat. Studies have shown that something as simple as a change in routine can negatively impact a cat’s immune system and make it sick. Even a healthy cat can be affected!

12. Cats really do have 9 lives, and it’s thanks to their interesting bodies. Cats have a “straightening reflex,” meaning that some of the tiny balancing-organs in their ears help tell a cat when they’ll hit the ground and how to land on their feet. 

13. At night, cats often choose to sleep in spots that are high-up and hidden in an effort to remain unseen by potential predators. This is just more proof that modern-day cats are not so different from cats in ancient times!

14. We all know that people can be allergic to cats, but did you know that some cats can be allergic to people? It’s estimated that approximately 1 in 200 cats suffers from asthma caused by dusty and unkempt living conditions. Luckily, cat inhalers exist.

15. If you’ve stepped on your cat’s tail, the high-pitched shriek and bared fangs you get in return is exactly what you’d see in a stray. A cat’s DNA never changes, so when threatened they revert right back to the wild ways of their ancestors. 

16. Humans are unique in how we all have different fingerprints, and the same can be said for cats…sort of. Believe it or not, the sure-fire identifier for a cat is actually its nose! Who knew those little noses were so complex?

17. It may sound like the only thing your cat does is meow and purr, but felines can actually produce about 100 sounds! This certainly furthers the “cats are smarter than dogs” argument, considering how dogs only produce about 10 sounds.

18. Cats need seven times less light than humans to see, especially during the daylight hours. This explains why some cats naturally gravitate towards dimly-lit rooms or closets. It’s also why they’re more energetic at night — they can simply see things easier!

19. There’s another reason cats are so bendy, and it’s not because they’ve been exercising! Felines are born without clavicles, which means they don’t have to worry about bulky bones impeding their movement. This makes them experts when it comes to slinking through narrow passages!

20. If your cats aren’t BBFs, there’s a reason why. Cats develop a “secret language” with humans, a language they do not share with any other cat living in the same space. This means no cuddling and no mingling — they’re basically just acquaintances!

Plenty of cats share their living spaces with a dog, too, because there’s a lot of overlap with cat and dog people. That’s why even feline aficionados are brushing up on these wild dog facts.

1. The word “puppy” is a relatively new addition to the English language. A variation on the French word “poupeé,” meaning doll or toy, it caught on in the late 1500s. Before that? Britons referred to baby dogs by the not-so-catchy term “whelps.”


2. Puppies sleep a ton — sometimes up to 20 hours per day — and for good reason. Rest is essential for their developing body and mind. Even when they reach maturity, dogs catch quite a few z’s each day, usually between 12 and 14 hours.

3. Just like humans, young dogs have baby teeth that fall out and eventually get replaced by an adult set. However, there is still no evidence that any kind of dog tooth fairy exists.

4. Depending on the breed, dogs can have vastly different sized litters. Bigger canines usually have bigger litters, as a rule of thumb. A Neapolitan mastiff owns the current record for giving birth to 24 puppies in 2011.

The West Australian / Ian Munro

5. Can dogs inspire great works of art? Hamilton composer and star Lin-Manuel Miranda would certainly say so. His stage ballad “Dear Theodosia” started out as an ode to his dog Tobillo, a stray pup he adopted in 2011.

6. If you’ve ever met a newborn puppy, you’ll notice that their eyes and ears don’t open for a couple of weeks. This is because, compared to other mammals, gestation periods for dogs are pretty short. As a result, puppies are born not quite fully developed!

7. Rolling Stones guitar hero Keith Richards smuggled a number of things past customs, cough cough, but his cutest contraband was a puppy. After sneaking it past British authorities, he named the pooch Ratbag and treated him to a rock ‘n’ roll lifestyle.

Bent Rej

8. Sure, your dog is friendly, but have you ever worried that they’d like any old stranger just as much as you? One 2005 study will put your mind at ease. Researchers observed that canines are most responsive to their owners, proving there is a definite bond.

9. Sports teams aren’t the only ones with dog mascots. The Spanish city of Bilbao is synonymous with West Highland Terriers thanks to Puppy, a gigantic sculpture outside the Guggenheim Museum. The statue weighs 17 tons and is covered in living flowers.

10. Just like in humans, yawns are contagious among mature dogs — probably as an embedded form of social empathy. Curiously enough, this isn’t the case for puppies! They are undeveloped enough to not react to their owners’ yawns at all.


11. For famed novelist John Steinbeck, a dog really did eat his homework. In 1936, his teething puppy tore apart his lone manuscript for Of Mice and Men. The frustrated author had to rewrite those chapters, much to the delight (or chagrin) of students everywhere.


12. Even though puppies from the same litter are similar, it’s extremely rare to find identical twin canines. The first confirmed case didn’t come until 2016 when a South African veterinarian determined two pups were genetically identical from sharing the same placenta.

Semantic Scholar

13. But twin puppies aren’t the only genetic canine copies out there. Scientists successfully cloned the first dog in 2005, and that practice has expanded into a niche industry of cloning families’ beloved pets — for the hefty price of $50,000.


14. It’s no coincidence that dogs seem sadder whenever you’re eating. They’ve evolutionarily adapted to raise their eyebrows and make their eyes bigger to improve their chances of guilting humans into tossing a scrap of food their way.


15. Seeing eye dogs aren’t the only employed pooches out there. Boston’s Museum of Fine Arts has trained a puppy named Riley to sniff out species of moths and beetles that destroy priceless artwork.

Smithsonian Magazine

16. Attention Dalmatian owners: don’t freak out when your puppies are born without any of the trademark spots! Those only start to pop up as the breed gets older. And Dalmatian puppies aren’t the only ones who’ve surprised owners with their coats…

17. In 2017, several dogs in the UK made headlines for giving birth to green puppies. Was this a rare mutation? Were the pups celebrating St. Patrick’s Day? No, it turns out their fur was temporarily dyed by biliverdin, a pigment naturally found in dog placentas.

18. Don’t freak out if your boss catches you scrolling through dog photos at work. A 2012 study concluded that looking at pictures of cute animals can actually help you concentrate afterward.


19. There was one warm and fuzzy result of the Cold War. Soviet Premier Nikita Kruschev knew that President John F. Kennedy was curious about Strelka, the Russian dog that went into space. As a gift, he sent JFK one of Strelka’s puppies. The Kennedys named her Pushinka, after the Russian word for “fluffy.”

Wikimedia Commons / Cecil W. Stoughton

20. JFK’s one-time political rival Richard Nixon also had a historical puppy moment. While running for Vice President in 1952, Tricky Dick came under fire for using campaign contributions for personal use. He denied these claims in a televised speech and said that the only gift he accepted was their family dog, Checkers.

21. Dogs don’t curl up while sleeping just to look cute, or even to feel more comfortable. This tendency is actually rooted in their instincts to protect their vital organs at night (and to stay warm, of course).


22. Some recent studies have found that dogs usually try to “go to the bathroom” in such a way that they’re aligned with the earth’s magnetic field. Both sexes defecate in the north or south direction, but only females prefer to urinate that way, too.


23. The idea that dogs only see in black and white is a total myth. They can actually perceive a wide range of colors, although it’s more limited than the spectrum that humans can see.


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